A noninvasive imaging technique for diabetic retinopathy (DR), using high-definition optical coherence tomography (HD-OCT) could be used to measure key preclinical markers of (DR) in patients with type 1 diabetes (T1D), according to a new study from Poland.
The study by sought measure retina thickness in patients with T1D compared with a control and evaluate what factors were linked with the advancement of DR. Researchers evaluated 111 patients, including 82 children and 29 adults who had lived with T1D an average of 6 years. Scans included a macular scan centered on the fovea, where the center of the field of vision is focused; thickness of the retinal nerve fiber layer (RNFL); several measures of the optic nerve head (ONH); and a measure of choroidal thickness. All measures were performed with HD-OCT Cirrus 5000.

Results showed negative correlations were found between a patient’s age and the neuroretinal rim area of the optic nerve; and between superior RNFL thickness and duration of diabetes. Positive correlation was noted between center thickness and standard deviation for average glycemia. Temporal choroidal thickness was positively correlated with age at examination.
The authors noted that more studies are needed on larger groups of patients, to understand how this Imaging technique for Diabetic Retinopathy could be helpful. While simultaneously measuring choroidal thickness and several other neurodegenerative parameters using HD-OCT “may be promising, “ and shows the potential usefulness of imaging as a diagnostic tool.