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Malignant Cancer Among Women and New-Onset Atrial Fibrillation

Recently a study says that there is increased risk of malignant cancer among women with newly developed atrial fibrillation. According to a recent study published in JACC: Cardio Oncology, cancer patients are more likely to develop atrial fibrillation (AF) than the general population, and the effect depends on the type of cancer. The type of cancer was assessed separately. This risk persisted after adjustments for other variables.

Multiple myeloma was associated with the highest risk of AF compared to control (RR 3.34; 95% CI 2.983.75), while gastric cancer was associated with the lowest risk (RR 1.27; 95% CI 1231.32). The relationship between atrial fibrillation (AF) and cancer is known but not well understood.

The purpose of this prospective study was to find out if the patients were cancer with greater risk of AF than non-cancer facilities. Cox proportional hazards models using time-updated covariates were constructed to evaluate the association of first AF with later cancer and to adjust for possible influencing factors. In contrast, among women with newly diagnosed cancer, the relative risk of AF increased only in the first 3 months (RR 4.67; 95% CI 2.857.64; P <0.001) but not later (RR 1.15; 95% CI 0.951, 39; P = 0.15). For this analysis, we excluded women with a history of AF (n = 879), malignancy (n = 52), or major cardiovascular event (n = 56) prior to randomization. Thus predisposing factor of malignant cancer among women is newly onset atrial fibrillation.

In a AF register, lacks a UNAF control control group, people are diagnosed with New-onset AF while admission has a higher rate of malignant cancer than the national average, with a rate A Danish national registry-based cohort study by Ostenfeld et al suggested that occult cancers were likely present at the time of AF diagnosis.12 Recently, Conen et al. reported an association association in a population-based cohort of US women from the Women’s Health Study.13 This association needs further demonstration in men and women, because of the temporal association between AF diagnosis. and subsequent cancer diagnosis can clarify the existence of a common etiology and can also guide clinicians about the high-risk window for cancer development. Therefore, the identification of AF as a potential cancer risk marker may have clinical and public health implications. In this study, we examined the association between recent-onset AF and subsequent cancer in a large population longitudinal cohort study of men and women in the Danish diet, cancer and health. Data, analytical methods and training materials will not be available to other researchers to recalculate the results or replication of the procedure.

A new diagnosis of atrial fibrillation (AF) is associated with a subsequent increased risk of cancer diagnosis. The risk of developing all types of cancer, colorectal cancer and lung cancer is especially high in the first 90 days after diagnosis. Metastatic cancer is likely at the time of diagnosis of AF.

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