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Women with atopic diseases are at 37% added risk of peripartum mental disorders

Women with a history of asthma, atopic dermatitis and allergic rhinitis have a 37 percent increased risk of  peripartum mental disorders, says a new study. The study conducted by Tai Ren, a postdoctoral student at the Shanghai Jiao Tong University School of Medicine, and her team found that poor control of atopic diseases during the peripartum period aggravates symptoms and may influence mental disorders through various causal pathways. Similarly, aggravated atopic symptoms may contribute to mental stress via severe pruritus or dyspnea-induced sleep disorder. Allergic reactions also may dysregulate the autoimmune system and trigger mental disorders, and peripheral inflammation may affect the brain, the researchers wrote. The study, published in Clinical and Translational Allergy, explained that the researchers looked into 9,37,244 primiparous women who had given birth in between 1978-2016 in Denmark. Interestingly, the researchers said, they found that while 1.2 percent of the women without asthma were affected by peripartum mental disorders such as depression and anxiety, among the women with atopic diseases, the count was 2.7 percent in the research population. Moreover, the researchers also added that asthma, atopic dermatitis and allergic rhinitis were specifically associated with increased risk for affective disorders. 

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