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ICS use found to have a positive impact on severe Covid patients with asthma

Inhaled corticosteroid (ICS) use was associated with a higher chance of early discharge of severe Covid patients from the hospital. A retrospective chart review of hospitalised asthma patients above 18 years testing positive for SARS-CoV2 from March to June 2020 by Farzan S Rebaza and team from the Northwell Health COVID-19 Research Consortium found that patients on ICS were 1.6 times more likely to be discharged on supplemental oxygen compared to patients not on ICS. The team revealed that the current study involved retrospective chart review of 908 inpatients with asthma testing positive for Covid and found that patients on ICS were 1.6 times more likely to be discharged on supplemental oxygen compared to patients not on ICS. Interestingly, the researchers also noted that men had poorer outcomes in terms of the need for mechanical ventilation, but death, discharge on oxygen, intensive care unit admission/days, and length of hospital stay were not significantly different between sexes. The investigators concluded that the outcomes of asthmatics hospitalised with COVID-19 were associated with sex and ethnicity, but ICS use was found strongly associated with cases of early discharge with supplemental oxygen and higher C-reactive protein levels.

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