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Life-threatening paradoxical bronchospasm overlooked in Asthma

A review of spirometry test results from US military veterans showed that a rare and potentially life-threatening adverse effect of bronchodilator therapy may be overlooked among patients with COPD or asthma. The review, presented by a fellow in the Department of Pulmonary and Critical Care at the University of Illinois and also the Jesse Brown Veterans Affairs Medical Center, Chicago at the annual meeting of the American College of Chest Physicians, stated that nearly 1.5% of the tests met the criteria for paradoxical bronchospasm, which refers to airway constriction that may rapidly occur after inhalation of a short-acting beta2 agonist (SABA) such as albuterol.

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