Low-dose aspirin did not significantly reduce the risk of stroke in a group of older, healthy adults, according to the study. During the trial, 4.7% of placebo participants and 4.6% of aspirin participants had their first stroke. While aspirin did not reduce the risk of ischemic stroke, it did considerably raise the chance of cerebral hemorrhage. Over a 5-year period, there were 2.5 fewer ischemic strokes but 3.5 more occurrences of cerebral hemorrhage for every 1000 people taking 100 mg of aspirin daily. When assessing the benefits of aspirin for primary stroke prevention in this age group, the extra risk of bleeding, particularly following head injuries that are common in older people, must be addressed. Overall, the results support the suggestion that low-dose aspirin not be prescribed.

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