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Natural Killer Cells: Potential Role in Reducing Neuropathic Pain through Neuronal Pruning

A recent study suggests that natural killer cells may play a role in reducing pain by assisting in the pruning of nerve cells. Pruning refers to the targeted elimination of functional synapses, which is essential for the formation of a healthy and adaptive brain. When neurons are damaged or diseased, they can cause pain by not functioning properly. Natural killer cells are known to target and remove unwanted cells in the body, such as cancer cells or infected cells. However, there is growing interest in understanding how these cells interact with the nervous system during injury or disease. The study provides evidence for a possible role of natural killer cells in neuropathic pain. One potential mechanism is that natural killer cells could help prune sensory nerves that have been damaged due to injury. This research sheds light on the potential therapeutic implications of natural killer cells in reducing pain and improving overall neurological health.

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