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Persistent Risk of Hepatic Decompensation and Hepatocellular Carcinoma After HCV Cure in Advanced Chronic Liver Disease Patients

According to a multicenter, retrospective study, individuals with advanced chronic liver disease (ACLD) who have been cured of the hepatitis C virus (HCV) have a continuing risk of hepatic decompensation and hepatocellular carcinoma (HCC). The study emphasizes the significance of long-term risk stratification following HCV treatment to guarantee proper resource usage. Dr. Georg Semmler and colleagues conducted the study, which included 2,335 individuals with compensated ACLD prior to HCV cure. After a median of 6 years of follow-up, 3.6% of patients suffered hepatic decompensation, and 7.8% developed HCC. The likelihood of both problems grew linearly over time, with about one out of every ten patients developing a liver-related incident despite an etiological cure. The researchers discovered many indicators related to liver disease to identify people at increased risk.

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