According to researchers, neuropathic pain, which affects around 10% of the global population, could be effectively treated with the atypical antidepressant tianeptine. This medication offers rapid and long-lasting pain relief with a lower risk of addiction. It is believed that tianeptine affects pain-related genes, leading to its potent effects even after the drug has left the body. Although tianeptine is not approved in the U.S. due to its interaction with opioid receptors, researchers argue for its potential use, highlighting its superior efficacy and reduced abuse potential compared to opioids.

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