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Human genome editing technology and new recommendations

Genome editing technology has been emerging in medical field . The World Health Organization (WHO) released two reports today that contain global guidelines for regulating the editing of the human genome, with a focus on ensuring the ethical and fair use of technology.

Should we use human gene editing? Who will get this technology? Who should make and implement rules for manipulating human genes? At the end of 2018, after He Jiankui, a biophysicist at Southern University of Science and Technology announced that he would use CRISPR technology to genetically modify twin embryos, the WHO commissioned an advisory committee to formulate international standards for processing the human genome.

He divided the “processing of the human genome” into five categories, depending on whether the processed cells are somatic cells or embryos, whether they are processed in the womb or after the person is born, and whether the processing is genetic or epigenetic. , And then deal with and prescribe the treatment or prevention of the disease. Or “improve” a person. Ennifer Doudna, a biochemist and CRISPR pioneer at the University of California, Berkeley, told STAT, “There is no single way to regulate genome editing on a global scale.” I am happy to announce that there are many different genome editing applications available. The application has its advantages and challenges. The second report contains recommendations in nine different areas related to the ethics of human genome editing, including human genome editing technology .

Registration requires people whose gene-editing technology is prohibited, illegal or unethical in their country of origin. Research, real estate, medical tourism, and WHO’s own values ​​and ethics.

The report stated: “WHO must cooperate with others to encourage relevant patent holders to ensure equal access to human genome manipulation interventions.” The genome includes new strategies for diagnosis, treatment and prevention of genetic diseases, new therapies for infertility, and increased resistance. Pathological new methods, contributions to vaccine development, and a better understanding of human biology. The human genome, the genome of the human embryo, changes and can be passed on to offspring. These reports guide how to manage and monitor human genome editing in nine different areas, including human genome record editing, international research and medical travel, illegal, unregistered, unethical or unsafe research.

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