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Links between IL-13 and reduced COVID effects in asthmatics

Th2 cytokine IL-13 appeared to play a significant role in protecting people with allergic asthma against the damaging effects of SARS-CoV-2 infection. According to the findings of a study published in the journal Proceedings of the National Academy of Sciences, IL-13 upregulated genes control glycoprotein synthesis, as well as the amount of virus inside cells and cell-to-cell viral transmission. The study,  conducted by Dr Camille Ehre, an assistant professor of paediatrics at the University of North Carolina School of Medicine, and colleagues, said that they observed IL-13 significantly affecting viral entry into cells, replication inside cells and virus spread.


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