Patients with severe pulmonary hypertension (PH) and chronic obstructive pulmonary disease (COPD) can now be identified using three important clinical variables. According to a recent study, published in CHEST,  by a team led by Gabor Kovacs, MD, associate professor of pulmonology, Medical University of Graz, Austria, systolic pulmonary arterial pressure (sPAP) ≥ 56 mmHg estimated by echocardiography, N-terminal pro-brain natriuretic peptide (NT-proBNP) plasma levels ≥ 650 pg/mL and the ratio of the main pulmonary artery/ascending aorta diameter at the tubular site (PA/Ao-ratio) in chest CT ≥ 0.93 are the three clinical variables included in the prediction model, which can be measured non-invasively.